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Researchers found that participants investing in this drug for the year, lost weight within four weeks and have kept the extra weight off through the 56 weeks with the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more efficient and safer.
Combo-pilling could be the newest fad or in addition to this the newest into the future under scrutiny and therefore it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is now popular may be the fact that by right now there aren't any long term prescription slimming capsules that have been approved by the FDA apart from orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.
Seizures really are a side effect with Contrave and really should not be taken in people with seizure disorders. The drug may also raise blood pressure and heartbeat, and must not be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before commencing the drug and throughout therapy using the drug.
The FDA also warned that Contrave can raise blood pressure and heart rate and must stop used in patients with uncontrolled high blood pressure levels, along with by anyone with heart-related and cerebrovascular (blood vessel dysfunction impacting the mind) disease. Patients using a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded through the clinical trials. Those taking Contrave should have their heart-rate and pulse monitored regularly. In addition, considering that the compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients towards the increased probability of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking.
"This could be the first drug I'm mindful of that targets the appetite and reward centres within the brain," he said.